Like any treatment there are risks however PRP has proven to have far less risks associated with its implementation. You can have pain at the injection site, bleeding, bruising or a potential infection. There is a slight possibility of an allergic reaction to the solution; there is slight risk of injury to a nerve or muscle, itching or redness at the injection site, nausea, dizziness or basic discomfort.

There is a necessary recovery period to anticipate after you receive a PRP injection. This involves swelling and possible bruising due to the inflammatory response caused by PRP. You can expect the swelling to go down in about 3 days to a week. You can minimize these effects by applying cold compresses, arnica cream, and keeping your head elevated. You can expect to see noticeable changes within 3 to 4 weeks following treatment. Softening of the lines and wrinkles, volume added to deflated areas, and a fuller, more toned looking complexion can result. You may continue to see improvements for up to one year. Some may need two to three treatments to achieve optimal results, however many times, only one is necessary.

If physicians use a product for an indication not in the approved labeling, they have  to inform the patient, adhere to good medical practice and have the responsibility  to be well informed about the product, to base its use on firm scientific rationale  and on sound medical evidence and to maintain records of the product’s use and  effects (source: www.fda.gov)